Noncoding miRNAs bridge virus infection and host autophagy in shrimp in vivo.
Identifieur interne : 000786 ( Main/Exploration ); précédent : 000785; suivant : 000787Noncoding miRNAs bridge virus infection and host autophagy in shrimp in vivo.
Auteurs : Yaodong He [République populaire de Chine] ; Yuechao Sun [République populaire de Chine] ; Xiaobo Zhang [République populaire de Chine]Source :
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology [ 1530-6860 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- génétique : microARN.
- métabolisme : microARN.
- physiologie : Autophagie, Virus de type 1 du syndrome des taches blanches.
- virologie : Penaeidae.
- Animaux, Interactions hôte-pathogène.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : MicroRNAs.
- chemical , metabolism : MicroRNAs.
- physiology : Autophagy, White spot syndrome virus 1.
- virology : Penaeidae.
- Animals, Host-Pathogen Interactions.
Abstract
Autophagy is known to be involved in viral infection. However, the relationship between autophagy and viral infection has not been characterized. MicroRNAs (miRNAs), important regulators of gene transcription, play central roles in many biologic processes, including autophagy and viral infection. It was therefore of interest to investigate the miRNAs regulating viral infection and host autophagy. In this study the viral infection (white spot syndrome virus, WSSV) correlated positively with the host autophagy in shrimp. Two host miRNAs (miR-71 and -13b) had significant effects on viral infection and host autophagy. MiR-71 regulated the viral infection and host autophagy by targeting the host calcification-associated peptide-1 (cap-1) gene. MiR-13b targeted the host knickkopf gene to simultaneously regulate viral infection and host autophagy. When the expressions of miR-71 and -13b were silenced in shrimp, the autophagy could not be induced by WSSV infection and the autophagy induction did not influence the virus replication, indicating that miR-71 and -13b were necessary for the viral infection and host autophagy. In this context, the findings of this study revealed a novel mechanism of miRNAs bridging the viral infection and host autophagy in vivo-He, Y., Sun, Y., Zhang, X. Noncoding miRNAs bridge virus infection and host autophagy in shrimp in vivo.
DOI: 10.1096/fj.201601141RR
PubMed: 28330853
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Noncoding miRNAs bridge virus infection and host autophagy in shrimp <i>in vivo</i>.</title><author><name sortKey="He, Yaodong" sort="He, Yaodong" uniqKey="He Y" first="Yaodong" last="He">Yaodong He</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author><author><name sortKey="Sun, Yuechao" sort="Sun, Yuechao" uniqKey="Sun Y" first="Yuechao" last="Sun">Yuechao Sun</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author><author><name sortKey="Zhang, Xiaobo" sort="Zhang, Xiaobo" uniqKey="Zhang X" first="Xiaobo" last="Zhang">Xiaobo Zhang</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China zxb0812@zju.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28330853</idno><idno type="pmid">28330853</idno><idno type="doi">10.1096/fj.201601141RR</idno><idno type="wicri:Area/Main/Corpus">000843</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000843</idno><idno type="wicri:Area/Main/Curation">000843</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000843</idno><idno type="wicri:Area/Main/Exploration">000843</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Noncoding miRNAs bridge virus infection and host autophagy in shrimp <i>in vivo</i>.</title><author><name sortKey="He, Yaodong" sort="He, Yaodong" uniqKey="He Y" first="Yaodong" last="He">Yaodong He</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author><author><name sortKey="Sun, Yuechao" sort="Sun, Yuechao" uniqKey="Sun Y" first="Yuechao" last="Sun">Yuechao Sun</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author><author><name sortKey="Zhang, Xiaobo" sort="Zhang, Xiaobo" uniqKey="Zhang X" first="Xiaobo" last="Zhang">Xiaobo Zhang</name><affiliation wicri:level="4"><nlm:affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China zxb0812@zju.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName><orgName type="university">Université de Zhejiang</orgName></affiliation></author></analytic><series><title level="j">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</title><idno type="eISSN">1530-6860</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Autophagy (physiology)</term><term>Host-Pathogen Interactions (MeSH)</term><term>MicroRNAs (genetics)</term><term>MicroRNAs (metabolism)</term><term>Penaeidae (virology)</term><term>White spot syndrome virus 1 (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term><term>Autophagie (physiologie)</term><term>Interactions hôte-pathogène (MeSH)</term><term>Penaeidae (virologie)</term><term>Virus de type 1 du syndrome des taches blanches (physiologie)</term><term>microARN (génétique)</term><term>microARN (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>MicroRNAs</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>MicroRNAs</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>microARN</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>microARN</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Autophagie</term><term>Virus de type 1 du syndrome des taches blanches</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Autophagy</term><term>White spot syndrome virus 1</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Penaeidae</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Penaeidae</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Host-Pathogen Interactions</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Interactions hôte-pathogène</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Autophagy is known to be involved in viral infection. However, the relationship between autophagy and viral infection has not been characterized. MicroRNAs (miRNAs), important regulators of gene transcription, play central roles in many biologic processes, including autophagy and viral infection. It was therefore of interest to investigate the miRNAs regulating viral infection and host autophagy. In this study the viral infection (white spot syndrome virus, WSSV) correlated positively with the host autophagy in shrimp. Two host miRNAs (miR-71 and -13b) had significant effects on viral infection and host autophagy. MiR-71 regulated the viral infection and host autophagy by targeting the host calcification-associated peptide-1 (<i>cap-1</i>) gene. MiR-13b targeted the host knickkopf gene to simultaneously regulate viral infection and host autophagy. When the expressions of miR-71 and -13b were silenced in shrimp, the autophagy could not be induced by WSSV infection and the autophagy induction did not influence the virus replication, indicating that miR-71 and -13b were necessary for the viral infection and host autophagy. In this context, the findings of this study revealed a novel mechanism of miRNAs bridging the viral infection and host autophagy <i>in vivo</i>-He, Y., Sun, Y., Zhang, X. Noncoding miRNAs bridge virus infection and host autophagy in shrimp <i>in vivo.</i></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28330853</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>18</Day></DateCompleted><DateRevised><Year>2018</Year><Month>01</Month><Day>26</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1530-6860</ISSN><JournalIssue CitedMedium="Internet"><Volume>31</Volume><Issue>7</Issue><PubDate><Year>2017</Year><Month>07</Month></PubDate></JournalIssue><Title>FASEB journal : official publication of the Federation of American Societies for Experimental Biology</Title><ISOAbbreviation>FASEB J</ISOAbbreviation></Journal><ArticleTitle>Noncoding miRNAs bridge virus infection and host autophagy in shrimp <i>in vivo</i>.</ArticleTitle><Pagination><MedlinePgn>2854-2868</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1096/fj.201601141RR</ELocationID><Abstract><AbstractText>Autophagy is known to be involved in viral infection. However, the relationship between autophagy and viral infection has not been characterized. MicroRNAs (miRNAs), important regulators of gene transcription, play central roles in many biologic processes, including autophagy and viral infection. It was therefore of interest to investigate the miRNAs regulating viral infection and host autophagy. In this study the viral infection (white spot syndrome virus, WSSV) correlated positively with the host autophagy in shrimp. Two host miRNAs (miR-71 and -13b) had significant effects on viral infection and host autophagy. MiR-71 regulated the viral infection and host autophagy by targeting the host calcification-associated peptide-1 (<i>cap-1</i>) gene. MiR-13b targeted the host knickkopf gene to simultaneously regulate viral infection and host autophagy. When the expressions of miR-71 and -13b were silenced in shrimp, the autophagy could not be induced by WSSV infection and the autophagy induction did not influence the virus replication, indicating that miR-71 and -13b were necessary for the viral infection and host autophagy. In this context, the findings of this study revealed a novel mechanism of miRNAs bridging the viral infection and host autophagy <i>in vivo</i>-He, Y., Sun, Y., Zhang, X. Noncoding miRNAs bridge virus infection and host autophagy in shrimp <i>in vivo.</i></AbstractText><CopyrightInformation>© FASEB.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>He</LastName><ForeName>Yaodong</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Yuechao</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xiaobo</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>College of Life Sciences and Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Zhejiang University, Hangzhou, China zxb0812@zju.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>03</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>FASEB J</MedlineTA><NlmUniqueID>8804484</NlmUniqueID><ISSNLinking>0892-6638</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D035683">MicroRNAs</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001343" MajorTopicYN="N">Autophagy</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054884" MajorTopicYN="N">Host-Pathogen Interactions</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D035683" MajorTopicYN="N">MicroRNAs</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D033561" MajorTopicYN="N">Penaeidae</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D046848" MajorTopicYN="N">White spot syndrome virus 1</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">WWSV</Keyword><Keyword MajorTopicYN="Y">interaction</Keyword><Keyword MajorTopicYN="Y">rapamycin</Keyword><Keyword MajorTopicYN="Y">target gene</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>10</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28330853</ArticleId><ArticleId IdType="pii">fj.201601141RR</ArticleId><ArticleId IdType="doi">10.1096/fj.201601141RR</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Zhejiang</li></region><settlement><li>Hangzhou</li></settlement><orgName><li>Université de Zhejiang</li></orgName></list><tree><country name="République populaire de Chine"><region name="Zhejiang"><name sortKey="He, Yaodong" sort="He, Yaodong" uniqKey="He Y" first="Yaodong" last="He">Yaodong He</name></region><name sortKey="Sun, Yuechao" sort="Sun, Yuechao" uniqKey="Sun Y" first="Yuechao" last="Sun">Yuechao Sun</name><name sortKey="Zhang, Xiaobo" sort="Zhang, Xiaobo" uniqKey="Zhang X" first="Xiaobo" last="Zhang">Xiaobo Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/RapamycinFungusV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000786 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000786 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= RapamycinFungusV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28330853
|texte= Noncoding miRNAs bridge virus infection and host autophagy in shrimp in vivo.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28330853" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a RapamycinFungusV1
| This area was generated with Dilib version V0.6.38. |  |